Predictive Factors for the Peri-operative Outcome of Ureteroscopic Lithotripsy for Proximal Ureteric Stones

  • Udita Mishra Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Anil Shrestha Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Parash Mani Shrestha Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Robin Bahadur Basnet Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Arvind Kumar Shah Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Chittaranjan Shah Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Surendra Basnet Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal
  • Baikuntha Adhikari Department of Urology, National Academy of Medical Sciences, Bir Hospital, Mahabouddha, Kathmandu, Nepal

Abstract

Background: Proximal ureteric stones are considered one of challenging location for lithotripsy using semirigid ureteroscopes. Aim of the study was to assess clinical and radiological characteristics associated with outcome of lithotripsy using semirigid ureteroscope for proximal ureteric stones.
Methods: Prospective observational study was done on patients who underwent semirigid ureteroscopic lithotripsy for proximal ureteric stone. Stone and ureteral mormphomeric parameters were documented from computed tomography urogram. Stone free status and complication rates were studied. To determine predictive factors for outcomes, multivariate regression analysis and receiver operative curve were used.
Results: One hundred patients were included in study. Demographic characteristics, stone size, density and mode of lithotripsy had no impact on stone free rate or complications. The mean ureteral wall thickness(p = 0.002), distance of stone from pelvi-ureteric junction(p = 0.005), degree of hydronephrosis(p = 0.0001) and peri-ureteric fat stranding (p = 0.038) were found to have significant association with stone free rate on univariate analysis. On multivariate analysis, mild hydronephrosis(p = 0.003) and distance of stone from pelvi-ureteric junction(p = 0.022) were significant for stone free rate.
Conclusions: Mean ureteral wall thickness, stone distance from pelvi-ureteric junction, presence of peri-ureteric fat stranding and hydronephrosis affect stone free rate on univariate analysis. On multivariate analysis for stone free rate, stone distance from pelvi-ureteric junction and mild hydronephrosis were significant. There was no significant impact of any stone or ureteral morphometry on complication rate.
Keywords: Complications; proximal ureteric stone; semirigid ureteroscopic lithotripsy; stone free rate

Published
2023-03-10
How to Cite
MishraU., ShresthaA., ShresthaP. M., BasnetR. B., ShahA. K., ShahC., BasnetS., & AdhikariB. (2023). Predictive Factors for the Peri-operative Outcome of Ureteroscopic Lithotripsy for Proximal Ureteric Stones. Journal of Nepal Health Research Council, 20(3), 761-767. https://doi.org/10.33314/jnhrc.v20i3.4608