Trends in Surgical Management of Esophageal Cancer

  • Binay Thakur Department of Surgical Oncology. BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal
  • Mukti Devkota Department of Surgical Oncology. BP Koirala Memorial Cancer Hospital, Bharatpur, Nepal
  • Asha Thapa Bharatpur Hospital Nursing College, Nepal
DOI: https://doi.org/10.33314/jnhrc.v20i4.4202

Abstract

Background: Management of esophageal cancer has changed to a combined modality approach over the past two decades due to poor outcome. Recently, multimodal treatment has become the standard practice. The aim of this study was to evaluate the changing trends in management and outcomes of esophagectomy over 15 years from a single center in Nepal.
Methods: Patients with squamous cell carcinoma and adenocarcinoma of esophagus/ gastroesophageal junction who underwent surgery between 2001-2018 were analyzed. Patients were grouped into three successive 5-year periods.
Results: 547 patients underwent esophagectomy during 2001-2018. There was increased trend of neoadjuvant treatment from 9-13% to 52% (p<.001) and minimally invasive surgery (MIS) from 0% to 80% (p<.001). 30-day mortality decreased from 8% to 1% (p=.01). The 5-overall survival was 24% which increased from 17% to 27% (p=.003).
Conclusions: Long term outcome has improved over last 15 years with decreasing mortality which appears to be due to incorporation of MIS and neoadjuvant treatment.
Keywords: Esophagectomy; esophageal cancer; multimodality therapy

Published
2023-07-20
How to Cite
ThakurB., DevkotaM., & ThapaA. (2023). Trends in Surgical Management of Esophageal Cancer. Journal of Nepal Health Research Council, 20(4), 868-874. https://doi.org/10.33314/jnhrc.v20i4.4202
Issue
Vol. 20 No. 4 (2022): Issue 57 Oct-Dec, 2022
Section
Original Article

Copyright (c) 2023 Binay Thakur, Mukti Devkota, Asha Thapa

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