Case of Late Recurrence in Early Stage Epithelial Ovarian Cancer

Abstract

Epithelial ovarian canceris usually diagnosed in late stage with high recurrence rate and fatality. Long term survival in late recurrence is not very common. We present a case of 66 year woman who had come in early stage of epithelial ovarian cancer. She survived despite having recurrence after 13 years following staging laparotomy with TAH with BSO with infracolic omentectomy and six cycles of adjuvant chemotherapy in 2007. She underwent secondary cytoreduction twice, first in 2013 and second in 2020 after she developed large pelvic mass. First secondary cytoreduction histopathology was inclusion cyst and second time it serous adencarcinoma grade III consistent with the histopathology of 2007. Both times she received chemotherapy after secondary cytoreduction including neoadjuvant chemotherapy (NACT) in 2020. She is doing well on follow up and is on oral etoposide.
Keywords: Chemotherapy; epithelial ovarian cancer; late recurrence; secondary cytoreduction